Company Filing History:
2 out of 504 
2 out of 1,206 
3 out of 832,680 Years Active: 1999-2003
Title: Roni J Bollag: Innovator in Genetic Research and Osteotropic Hormones
Introduction
Roni J Bollag is a notable inventor based in Martinez, GA (US), recognized for his contributions to genetic research and the study of osteotropic hormones. With a total of 5 patents, Bollag has made significant strides in understanding DNA mismatch repair genes and their implications in cancer susceptibility, as well as the role of glucose-dependent insulinotropic peptide (GIP) in bone density regulation.
Latest Patents
Bollag's latest patents include groundbreaking work on compositions and methods relating to DNA mismatch repair genes. This patent describes genomic sequences of human mismatch repair genes and gene products, along with methods for detecting mutations and polymorphisms in these genes. It also outlines techniques for diagnosing cancer susceptibility and identifying mismatch-repair-defective tumors. Notably, the patent provides sequences and methods related to human mutL homologs, specifically the hMLH1 and hPMS1 genes and their products.
Another significant patent focuses on glucose-dependent insulinotropic peptide for use as an osteotropic hormone. This research demonstrates the presence of GIP receptor mRNA and protein in normal bone and osteoblastic-like cell lines. The findings indicate that GIP stimulates an increase in cellular cAMP content and intracellular calcium in osteoblast-like cells, reflecting its anabolic actions on bone remodeling. The patent highlights GIP's potential therapeutic applications in inhibiting bone resorption and maintaining or increasing bone density.
Career Highlights
Throughout his career, Roni J Bollag has worked with various institutions, including Oregon Health & Science University. His research has contributed to a deeper understanding of genetic mechanisms and their applications in medicine. Bollag's innovative work has positioned him as a key figure in the fields of genetics and bone health.
Collaborations
Bollag has collaborated with esteemed colleagues such as Robert M Liskay and C Eric Bronner, further enhancing the impact of his research through shared expertise and insights.
Conclusion
Roni J Bollag's contributions to genetic research and osteotropic hormones have paved the way for advancements in cancer diagnostics and bone health therapies. His innovative patents reflect a commitment to scientific discovery and the betterment of human health.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.