The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 25, 2003

Filed:

Mar. 10, 1999
Applicant:
Inventors:

Robert M. Liskay, Lake Oswego, OR (US);

C. Eric Bronner, Portland, OR (US);

Sean M. Baker, Berkeley, CA (US);

Roni J. Bollag, Martinez, GA (US);

Richard D. Kolodner, San Diego, CA (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 1/600 ; C07K 1/618 ; C07K 1/632 ;
U.S. Cl.
CPC ...
C07K 1/600 ; C07K 1/618 ; C07K 1/632 ;
Abstract

Genomic sequences of human mismatch repair genes and gene products are described, as are methods of detecting mutations and/or polymorphisms in those genes. Also described are methods of diagnosing cancer susceptibility in a subject, and methods of identifying and classifying mismatch-repair-defective tumors. In particular, sequences and methods relating to human mutL homologs, hMLH1 and hPMS1 genes and gene products are provided.


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