The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 26, 2000
Filed:
Oct. 31, 1997
Applicant:
Inventors:
Robert M Liskay, Lake Oswego, OR (US);
C Eric Bronner, Portland, OR (US);
Sean M Baker, Portland, OR (US);
Roni J Bollag, Martinez, GA (US);
Richard D Kolodner, Jamaica Plain, MA (US);
Assignees:
Oregon Health Sciences University, Portland, OR (US);
Dana-Farber Cancer Institute, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; C07H / ; C12P / ;
U.S. Cl.
CPC ...
435-6 ; 435-71 ; 435 911 ; 435 912 ; 536 2433 ;
Abstract
Genomic sequences of human mismatch repair genes are described, as are methods of detecting mutations and/or polymorphisms in those genes. Also described are methods of diagnosing cancer susceptibility in a subject, and methods of identifying and classifying mismatch-repair-defective tumors. In particular, sequences and methods relating to human mutL homologs, hMLH1 and hPMS1 genes are provided.