Location History:
- Overbrook Hills, PA (US) (1987 - 1994)
- Newton, MA (US) (2001)
Company Filing History:
10 out of 4,770 
1 out of 832,680 Years Active: 1987-2001
Title: The Innovations of Ronald W. Ellis
Introduction
Ronald W. Ellis is a notable inventor based in Overbrook Hills, PA (US), recognized for his significant contributions to the field of biotechnology. With a total of 11 patents to his name, he has made remarkable advancements in the production of recombinant proteins and vaccine development.
Latest Patents
Among his latest patents is a method for increasing the production of disulfide bonded recombinant proteins by Saccharomyces cerevisiae. This innovative process enhances the yield of these proteins, which are crucial for therapeutic applications. The enzyme protein disulfide isomerase (PDI) plays a vital role in catalyzing the formation of disulfide bonds in proteins. Ellis's work involves constructing recombinant strains of yeast that overproduce either human PDI or yeast PDI, leading to significantly increased secretion of disulfide bonded proteins. Another notable patent is related to a vaccine strain of varicella-zoster virus (VZV), which has been tested in clinical trials and is capable of preventing chickenpox in children. This recombinant virus has been modified to express an immunogenic polypeptide from another human pathogen, making it a valuable tool for vaccine development.
Career Highlights
Throughout his career, Ronald W. Ellis has worked with prominent companies, including Merck & Company, Inc. His expertise in biotechnology and protein engineering has positioned him as a leader in his field.
Collaborations
Ellis has collaborated with esteemed colleagues such as Robert S. Lowe and Paul M. Keller, contributing to the advancement of innovative solutions in biotechnology.
Conclusion
Ronald W. Ellis's contributions to the field of biotechnology through his patents and collaborations highlight his role as a significant inventor. His work continues to impact the development of therapeutic proteins and vaccines, showcasing the importance of innovation in science.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.