The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 1989
Filed:
Mar. 23, 1987
Applicant:
Inventors:
Ronald W Ellis, Overbrook Hills, PA (US);
Paul M Keller, Lansdale, PA (US);
Robert S Lowe, Harleysville, PA (US);
Andrew J Davison, Glasgow, GB;
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H / ; C12P / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
536 27 ; 435 91 ; 435 68 ; 435 70 ; 4351723 ; 4353171 ; 435320 ; 935 12 ;
Abstract
A gene of varicella-zoster virus (VZV) which encodes immunogenic outer surface viral proteins has been identified by DNA sequence analysis. This gene can hybrid select messenger RNA which encodes and expresses a protein which reacts with human convalescent zoster sera and with polyclonal monospecific antisera which neutralize viral infectivity. These proteins are useful for the preparation of a vaccine for VZV.