The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 1994
Filed:
Feb. 27, 1992
Applicant:
Inventors:
Ronald W Ellis, Overbrook Hills, PA (US);
Elliott Kieff, Brookline, MA (US);
Edward M Scolnick, Wynnewood, PA (US);
Robert S Lowe, Harleysville, PA (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
4351723 ; 4352351 ; 4353001 ; 424 89 ; 935 32 ; 935 57 ; 935 65 ;
Abstract
A vaccine strain of varicella-zoster virus (VZV), tested in clinical trials, is capable of preventing chickenpox in children. This virus has been modified by the introduction into its genome of heterologous DNA which encodes an immunogenic polypeptide of another human pathogen. This heterologous polypeptide is expressed in cells infected by the recombinant virus. Such recombinant VZV is useful as a vaccine for chickenpox as well as for heterologous pathogens.