Company Filing History:
7 out of 10,754 
2 out of 12 
1 out of 5,682 
Years Active: 2002-2019
Title: The Innovative Contributions of Rolf Schmid
Introduction: Rolf Schmid, an accomplished inventor based in Stuttgart, Germany, has made significant contributions to the field of biochemistry with a focus on hydroxysteroid dehydrogenases. With a robust portfolio of 11 patents, Schmid’s work is characterized by innovative approaches to enzymatic processes, particularly in the synthesis of compounds beneficial in medical applications.
Latest Patents: Among Schmid's recent patents are two notable inventions related to hydroxysteroid dehydrogenases. The first patent focuses on novel 7β-hydroxysteroid dehydrogenases, which can be obtained from specific bacterial strains. This invention includes the sequences that encode these enzymes, methods for their production, and applications in the enzymatic conversion of cholic acid compounds, particularly in the production of ursodeoxycholic acid (UDCS). The second patent introduces 12α-hydroxysteroid dehydrogenase knockout mutants, covering a range of advancements from expression cassettes to methods for the enzymatic oxidation and reduction of steroids. These innovations aim to enhance the production of UDCS through enzyme-catalyzed processes.
Career Highlights: Rolf Schmid's career is highlighted by his work with prominent companies such as BASF Aktiengesellschaft and Pharmazell GmbH. His professional journey reflects a dedication to chemical and pharmaceutical advancements, engaging in projects that bridge industrial applications with cutting-edge research.
Collaborations: Throughout his career, Schmid has collaborated with esteemed colleagues like Bernhard Hauer and Juergen Pleiss. These collaborations have enriched his research and expanded the impact of his inventions, fostering a collaborative environment that promotes innovation.
Conclusion: Rolf Schmid stands out as a remarkable inventor in the field of biochemistry. With his significant contributions to the development of hydroxysteroid dehydrogenases, he has pushed the boundaries of enzymatic transformation and pharmaceutical production. His work will undoubtedly continue to influence future research and innovations in the medical field.