Location History:
- Seattle, WA (US) (2002 - 2014)
- Dallas, TX (US) (2012 - 2020)
Company Filing History:
18 out of 5,445 
1 out of 8,370 
1 out of 3,092 
Years Active: 2002-2020
Title: Innovations by Rolf A. Brekken: Pioneering Cancer Treatment and Therapeutics
Introduction
Rolf A. Brekken, based in Seattle, WA, is a distinguished inventor with a significant contribution to the field of medical sciences. With 19 patents to his name, Brekken's innovative work primarily focuses on cancer therapeutics and various disease treatments.
Latest Patents
Among Brekken's latest inventions is the patent for "Cancer specific lipid targeted peptidomimetics." This innovative peptoid targets phosphatidylserine, binding specifically to cancer cells. Notably, a dimer version of this peptoid has shown promise in decreasing cancer cell viability and enhancing the efficacy of docetaxel, a commonly used chemotherapy drug. Furthermore, this peptoid is versatile and can be utilized in diagnosing and treating conditions such as cancer, viral infections, and diabetes.
Another remarkable patent is on "Small-molecule inhibitors targeting discoidin domain receptor 1." This invention includes compounds effective in inhibiting enzymatic activity related to this receptor, offering new therapeutic avenues for treating inflammation, liver fibrosis, kidney fibrosis, lung fibrosis, skin scars, atherosclerosis, and cancer.
Career Highlights
Throughout his career, Rolf A. Brekken has collaborated with prestigious institutions, including the University of Texas System and the Massachusetts Institute of Technology. His innovative research has led to significant advancements in therapeutic strategies against debilitating diseases.
Collaborations
Brekken has worked alongside notable colleagues like Philip E. Thorpe and Sophia Ran, contributing to the collective effort in realizing groundbreaking medical advancements. These collaborations have enriched his research, facilitating the development of solutions for pressing healthcare challenges.
Conclusion
Rolf A. Brekken exemplifies innovation in medical research, particularly in cancer treatment and therapeutic interventions. His patents reflect a dedication to advancing healthcare solutions, demonstrating the potential to change the landscape of medical treatments for various diseases. As the field continues to evolve, the contributions of inventors like Brekken will undoubtedly play a pivotal role in shaping the future of medicine.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.