The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2019
Filed:
Oct. 21, 2015
The Board of Regents of the University of Texas System, Austin, TX (US);
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, CN;
Rolf A. Brekken, Dallas, TX (US);
Ke Ding, Guangzhou, CN;
Xiaomei Ren, Guangzhou, CN;
Zhengchao Tu, Guangzhou, CN;
Zhen Wang, Guangzhou, CN;
Kristina Y. Aguilera, Dallas, TX (US);
The Board of Regents of the University of Texas System, Austin, TX (US);
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, CN;
Abstract
Compounds of formula (I), their pharmaceutically acceptable salts and stereoisomers thereof, as well as application in effectively inhibiting the enzymatic activity of discoidin domain receptor 1 and can be used as new therapeutic agents for preventing and treating e.g. inflammation, liver fibrosis, kidney fibrosis, lung fibrosis, skin scar, atherosclerosis, and cancer. The compound of formula I is: wherein the variables are as defined herein.