The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 05, 2018
Filed:
Oct. 22, 2015
Applicant:
The Board of Regents of the University of Texas System, Austin, TX (US);
Inventors:
Thomas M. Wilkie, Dallas, TX (US);
Rolf A. Brekken, Dallas, TX (US);
Assignee:
The Board of Regents of the University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01K 67/027 (2006.01); A61K 31/337 (2006.01); A61K 31/7068 (2006.01); A61K 31/366 (2006.01); A61K 31/502 (2006.01); A61K 49/00 (2006.01); C12Q 1/68 (2018.01); G01N 33/574 (2006.01); A61K 31/00 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0278 (2013.01); A01K 67/0275 (2013.01); A61K 31/00 (2013.01); A61K 31/337 (2013.01); A61K 31/366 (2013.01); A61K 31/502 (2013.01); A61K 31/7068 (2013.01); A61K 49/0008 (2013.01); C12Q 1/6886 (2013.01); G01N 33/57438 (2013.01); A01K 2217/056 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0331 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01);
Abstract
The present disclosure relates to methods for screening compounds for treating pancreatic ductal adenocarcinoma (PDA) using a mouse model with an Rgs16::GFP reporter. Also described are combination therapies for treating pancreatic ductal adenocarcinoma (PDA) using taxanes, gemcitabine and an Axl kinase inhibitor.