Roland Riek

Title: Innovations and Contributions of Inventor Roland Riek

Introduction

Roland Riek is a notable inventor based in La Jolla, California. He has made significant contributions to the field of biochemistry and pharmacology, holding a total of three patents. His work focuses on the development of modulators for G-protein coupled receptors and methods for producing recombinant proteins.

Latest Patents

One of Roland Riek's latest patents is titled "Structure-based modulators of B1 G-protein coupled receptors." This invention relates to methods for identifying modulators of B1 G-protein coupled receptors, including the identification of antagonists or agonists of the corticotropin-releasing factor receptor 2 (CRFR2). Additionally, it discusses the three-dimensional structure of CRFR2 as a basis for rational drug design. Another significant patent is "Compositions and methods for producing recombinant proteins," which discloses a class of integral membrane proteins known as Mistic polypeptides. This patent includes methods for using Mistic polypeptides to produce and isolate recombinant proteins, particularly eukaryotic integral membrane proteins that are challenging to express in bacterial systems.

Career Highlights

Throughout his career, Roland Riek has worked with prestigious organizations, including the Salk Institute for Biological Studies and the Research Development Foundation. His research has contributed to advancements in drug design and protein production, making a lasting impact in the scientific community.

Collaborations

Roland Riek has collaborated with esteemed colleagues such as Jean E. F. Rivier and Jean Claude Reubi. These collaborations have further enriched his research and innovations in the field.

Conclusion

Roland Riek's contributions to science through his patents and collaborations highlight his role as an influential inventor in biochemistry. His work continues to pave the way for advancements in drug development and protein engineering.