Location History:
- Zurich, CH (2004 - 2010)
- Rochester, MN (US) (2009 - 2019)
Company Filing History:
Years Active: 2004-2019
Title: Innovations of Roberto Cattaneo
Introduction
Roberto Cattaneo is a notable inventor based in Rochester, MN (US). He has made significant contributions to the field of gene transfer technology, holding a total of 9 patents. His work focuses on the development of retroviral vectors, which have important applications in targeted gene therapy.
Latest Patents
One of Cattaneo's latest patents is titled "Pseudotyping of retroviral vectors, methods for production and use thereof for targeted gene transfer and high throughput screening." This invention relates to the pseudotyping of retroviral vectors with heterologous envelope proteins derived from the Paramyxoviridae family. The invention is based on the unexpected finding that incorporating F and H proteins with truncated cytoplasmic tails into lentiviral vector particles enhances the transduction of cells. Furthermore, these pseudotyped vector particles enable targeted gene transfer into specific cell types by modifying a mutated and truncated H protein with a single-chain antibody or ligand directed against a cell surface marker of the target cell.
Career Highlights
Cattaneo has worked with prestigious organizations, including the Mayo Foundation for Medical Education and Research and the Paul-Ehrlich-Institut in Germany. His innovative work has positioned him as a key figure in the advancement of gene transfer technologies.
Collaborations
Throughout his career, Cattaneo has collaborated with esteemed colleagues such as Stephen James Russell and Frances Joanne Morling. These partnerships have contributed to the success and impact of his research.
Conclusion
Roberto Cattaneo's contributions to the field of gene transfer technology through his innovative patents and collaborations highlight his importance as an inventor. His work continues to influence advancements in targeted gene therapy.