Location History:
- Forth Worth, TX (US) (2012)
- Fort Worth, TX (US) (2009 - 2014)
Company Filing History:
3 out of 188 
2 out of 3,540 
Years Active: 2009-2014
Title: The Innovations of Robert R. Luedtke
Introduction
Robert R. Luedtke is a notable inventor based in Fort Worth, TX (US). He has made significant contributions to the field of pharmacology, particularly in the development of dopamine receptor antagonists and selective ligands. With a total of three patents to his name, Luedtke's work has implications for understanding and treating substance abuse disorders.
Latest Patents
Luedtke's latest patents include innovations related to dopamine receptor antagonists and partial agonists. These compounds are known to modulate the reinforcing and drug-seeking effects induced by cocaine and other abused substances. By introducing functionality into the butylamide linking chain of the 4-phenylpiperazine class of ligands, he has achieved improved receptor affinity, selectivity, and water solubility. Additionally, he has disclosed a series of linking-chain derivatives that incorporate functional groups such as OH or OAc, which are well tolerated at dopamine receptors and achieve high selectivity over other receptor types. Another significant patent describes a family of structurally rigid dopamine D3 receptor selective ligands, which have various structural formulas and substituents that enhance their effectiveness.
Career Highlights
Throughout his career, Robert R. Luedtke has worked with esteemed institutions, including the University of North Texas and the Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services. His research has contributed to advancements in the understanding of dopamine receptors and their role in addiction.
Collaborations
Luedtke has collaborated with notable colleagues such as Amy Hauck Newman and Peter Grundt. Their combined expertise has furthered the research and development of innovative pharmacological solutions.
Conclusion
Robert R. Luedtke's contributions to the field of pharmacology through his patents and collaborations highlight his role as an influential inventor. His work continues to impact the understanding and treatment of substance abuse disorders.