Company Filing History:
17 out of 647 
1 out of 6 Years Active: 1999-2017
Title: Robert P. Kimberly: Innovations in Antibody Research
Introduction
Robert P. Kimberly, an accomplished inventor based in Birmingham, AL, has made significant contributions to the field of antibody research, holding a remarkable total of 18 patents. His work has advanced the understanding of apoptosis and dysregulated cell growth, particularly in the context of cancer and autoimmune diseases.
Latest Patents
One of Kimberly's latest patents involves an antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor. This innovative antibody interacts with human DR5, producing both agonistic and antagonistic effects downstream of the receptor, which includes the inhibition of cell proliferation and apoptosis. The patent elucidates the nucleic acid sequences and amino acid sequences of anti-DR5 antibodies, as well as methods for generating vectors and cells that express these sequences. Applications of this innovation include the treatment of apoptosis-related diseases and addressing cases of dysregulated cell growth.
Another prominent patent from Kimberly focuses on agents and methods related to screening for resistance to DR5 and reducing such resistance when applying DR5 agonists. This method provides a way to reverse or prevent a target cell's resistance to death receptor agonists. Additionally, it details methods for selectively inducing apoptosis in target cells, which can be pivotal in treating subjects with cancer, autoimmune disorders, or inflammatory diseases. The patent further encompasses compositions containing agents that modulate CARD-containing proteins.
Career Highlights
Throughout his career, Robert P. Kimberly has held esteemed positions at notable institutions, including the UAB Research Foundation and the New York Society for the Relief of the Ruptured and Crippled. His work has not only produced groundbreaking patents but has also contributed significantly to advancing research in his fields of expertise.
Collaborations
Kimberly has collaborated with distinguished colleagues, including Tong Zhou and William J. Koopman. These collaborations have enriched his research, fostering innovation and paving the way for successful developments in antibody therapeutics.
Conclusion
Robert P. Kimberly's extensive portfolio of patents and his dedication to research exemplify his significant impact on the scientific community. His innovative approaches to antibody applications are poised to influence future treatments for various diseases, underscoring the importance of continued exploration in biotechnology and medicine.