Lansdale, PA, United States of America

Robert M Garbaccio

USPTO Granted Patents = 25 

 

Average Co-Inventor Count = 4.4

ph-index = 5

Forward Citations = 56(Granted Patents)


Location History:

  • Landsdale, PA (US) (2010)
  • West Point, PA (US) (2015)
  • Lansdale, PA (US) (2006 - 2024)

Company Filing History:


Years Active: 2006-2024

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25 patents (USPTO):

Title: The Innovative Contributions of Robert M. Garbaccio

Introduction

Robert M. Garbaccio, based in Lansdale, Pennsylvania, is a notable inventor with a remarkable portfolio of 25 patents. His work primarily focuses on biopharmaceutical innovations that have substantial implications for treating various metabolic disorders.

Latest Patents

Among his latest contributions are two significant patents:

1. **Phosphonate Linkers** - This patent describes phosphonate linkers and their utility in enhancing the cellular retention of compounds. The innovation highlights the effectiveness of these linkers in facilitating the delivery of compounds with passive cell permeability, thereby improving their therapeutic potential.

2. **Antibody Peptide Conjugates** - Garbaccio's next patent details antibody peptide conjugates (APCs) that exhibit agonist activity at both glucagon and glucagon-like peptide-1 receptors. These conjugates have been modified to resist cleavage by dipeptidyl peptidase IV, enhancing the in vivo half-life of the peptide analog. This innovation aims to provide treatment options for metabolic disorders such as diabetes, non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and obesity.

Career Highlights

Robert M. Garbaccio has made significant advancements in pharmaceutical research during his career, contributing to major companies such as Merck Sharp & Dohme Corporation and Merck & Company, Inc. His work has paved the way for developing new therapeutic strategies that hold promise for improving patient outcomes in metabolic health.

Collaborations

Throughout his career, Garbaccio has collaborated with prominent figures in the field, including Mark E. Fraley and Jeffrey Curtis Kern. These collaborations have fostered an environment of innovation, leading to breakthroughs with real-world applications.

Conclusion

Robert M. Garbaccio stands out as a distinguished inventor whose contributions, reflected in his numerous patents, have had a substantial impact on the pharmaceutical industry. His continued innovation in the realm of biopharmaceuticals showcases the importance of inventive thinking in addressing complex health challenges.

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