The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 17, 2023
Filed:
Sep. 24, 2020
Applicant:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Inventors:
Robert M. Garbaccio, Lansdale, PA (US);
Jeffrey C. Kern, Gilbertsville, PA (US);
James J. Mulhearn, Elkins Park, PA (US);
Philip E. Brandish, Needham, MA (US);
Assignee:
Merck Sharp & Dohme LLC, Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/54 (2017.01); A61K 47/68 (2017.01); C07F 9/38 (2006.01); C07F 9/40 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/548 (2017.08); A61K 47/6803 (2017.08); A61K 47/6849 (2017.08); A61K 47/6889 (2017.08); C07F 9/3839 (2013.01); C07F 9/40 (2013.01); A61P 29/00 (2018.01); A61P 35/00 (2018.01);
Abstract
Phosphonate linkers and their use for delivering compounds with passive cell permeability into a cell wherein the phosphonate group facilitates cellular retention of the compound are described.