Richard W Noreiks

Title: Innovations by Richard W. Noreiks: A Leader in Thermal Cycler Technology

Introduction

Richard W. Noreiks is a notable inventor based in Stratford, CT, who has made significant contributions to the field of biotechnology through his innovative designs. With a portfolio of eight patents, Noreiks has established himself as a key player in the development of advanced thermal cyclers, particularly for polymerase chain reaction (PCR) applications.

Latest Patents

One of Richard W. Noreiks's latest patents is a sophisticated thermal cycler for PCR. This instrument is designed to perform highly accurate PCR through an assembly that integrates a heated cover and an internal computer. The core of the device consists of a sample block, multiple Peltier thermoelectric devices, and a heat sink, all meticulously clamped together. The system utilizes a control algorithm that dynamically manages the current sent to the thermoelectric coolers, allowing for precise control over thermal performance. Notably, the sample temperature is computed rather than directly measured, using a design-specific model and equations, which enhances the efficiency and accuracy of thermal cycling.

The sample block constructed from low thermal mass silver ensures rapid temperature adjustments over a broad range. Moreover, the design includes a perimeter trench heat sink to minimize edge losses, along with a heated platen that aids in achieving thermal uniformity and preventing sample evaporation during cycles. The advanced control software includes calibration diagnostics, allowing for optimization of performance across different instruments. This level of interchangeability among assemblies, powered by on-board memory that characterizes their performance, is a unique aspect of Noreiks's invention.

Career Highlights

Throughout his career, Richard W. Noreiks has worked with several prestigious companies in the biotechnology field, including Applied Biosystems, LLC and PerkinElmer Corporation. His role in these organizations has positioned him to influence and shape the landscape of PCR technology significantly.

Collaborations

In addition to his professional journey, Noreiks has collaborated with esteemed colleagues such as John Girdner Atwood and Adrian Fawcett. These partnerships have fostered an environment of innovation and discovery, leading to advancements in the design and functionality of equipment used in genetic research and diagnostics.

Conclusion

Richard W. Noreiks's contributions to the field of biotechnology, particularly through his inventive thermal cycler technology, are invaluable. With eight patents to his name, his work not only reflects his expertise as an inventor but also contributes to the ongoing evolution of PCR methodologies in scientific research. His career continues to inspire new developments that push the boundaries of what is possible in biotechnology.