The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 2009

Filed:

Feb. 15, 2005
Applicants:

John G. Atwood, West Redding, CT (US);

Adrian Fawcett, Pleasanton, CA (US);

Keith S. Ferrara, Stratford, CT (US);

Paul M. Hetherington, Goldens Bridge, NY (US);

Richard W. Noreiks, Stratford, CT (US);

Douglas E. Olsen, New Fairfield, CT (US);

John R. Widomski, Shelton, CT (US);

Charles M. Wittmer, Trumbull, CT (US);

Inventors:

John G. Atwood, West Redding, CT (US);

Adrian Fawcett, Pleasanton, CA (US);

Keith S. Ferrara, Stratford, CT (US);

Paul M. Hetherington, Goldens Bridge, NY (US);

Richard W. Noreiks, Stratford, CT (US);

Douglas E. Olsen, New Fairfield, CT (US);

John R. Widomski, Shelton, CT (US);

Charles M. Wittmer, Trumbull, CT (US);

Assignee:

Applied Biosystems, LLC, Carlsbad, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01K 15/00 (2006.01); G01K 19/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method for performing highly accurate PCR employing an assembly, a heated cover and an internal computer. The assembly is made up of a sample block, a number of Peltier thermal electric devices and heat sink, clamped together. The sample block temperature is changed exclusively by the thermoelectric devices controlled by the computer. The control software includes calibration diagnostics which permit variation in the performance of thermoelectric coolers from instrument to instrument to be compensated for such that all instruments perform identically. The block heat sink assembly can be changed to another of the same or different design. The assembly carries the necessary information required to characterize its own performance in an on-board memory device, allowing the assembly to be interchangeable among instruments while retaining its precision operating characteristics. The instrument monitors the thermoelectric devices and warns of changes in resistance that may result in failure.


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