Company Filing History:
Years Active: 2001-2016
Title: Richard Jay Smeyne: Innovator in Biomedical Research
Introduction
Richard Jay Smeyne is a notable inventor based in Collierville, TN (US). He has made significant contributions to the field of biomedical research, particularly in the areas of cellular biology and pharmacology. With a total of 3 patents, his work has advanced our understanding of various biological processes.
Latest Patents
One of Richard's latest patents is a method for the detection of adenosine and its metabolites. This invention is a label-free, enzyme-free, and aptamer-free method for simultaneously measuring adenosine and its intracellular metabolites, such as AMP, ADP, and ATP, using high-pressure liquid chromatography coupled to an electrochemical detector (HPLC-ECD). Another significant patent involves non-human animals that have been manipulated to lack functional p19 and p27 proteins. This patent describes a p19-double null, p27-double null mouse, which exhibits bradykinesia, proprioceptive abnormalities, and seizure-like activity, typically dying 14-24 days after birth. Additionally, mammalian cells with the p19-double null, p27-double null genotype are characterized, along with methods for creating and utilizing these non-human knockout animals and cells.
Career Highlights
Richard Jay Smeyne is affiliated with St. Jude Children's Research Hospital, where he conducts his research. His work has been instrumental in advancing the understanding of genetic and cellular mechanisms in various diseases.
Collaborations
Richard has collaborated with notable colleagues, including Martine F Roussel and Frederique Zindy. These collaborations have further enriched his research and contributed to the scientific community.
Conclusion
Richard Jay Smeyne's innovative work in biomedical research has led to important advancements in the understanding of cellular processes and disease mechanisms. His contributions continue to impact the field significantly.