Richard J Mehigh

Title: **Innovator Spotlight: Richard J. Mehigh**

Introduction

Richard J. Mehigh, an accomplished inventor based in Oakville, MO, is recognized for his significant contributions to the field of biochemistry and protein purification. With seven patents to his name, Mehigh’s innovations demonstrate a commitment to advancing scientific techniques that enhance the extraction and isolation of cellular components.

Latest Patents

Among his notable inventions is the patent titled "Method for extracting a target product from a host cell employing zwitterionic detergent combinations." This invention presents lysis reagents, containers, methods, and kits designed for the efficient extraction or isolation of cellular components from host cells. The zwitterionic compounds highlighted in this patent facilitate this process, showcasing Mehigh's ingenuity in biotechnological applications.

Additionally, Mehigh holds a patent for "Affinity peptides and method for purification of recombinant proteins." This process outlines a method for separating fusion proteins from mixtures, utilizing a resin containing immobilized metal ions. By covalently linking the fusion protein to an affinity peptide associated with these metal ions, this method allows for selective elution and purification, further cementing Mehigh's role as a pioneer in protein purification technologies.

Career Highlights

Richard J. Mehigh currently contributes his expertise at Sigma-Aldrich Co. LLC, where he applies his innovative principles to real-world applications within the life sciences sector. His dedication to research and development plays a critical role in the company's advancements in biochemical products and services.

Collaborations

Throughout his career, Mehigh has collaborated with esteemed colleagues such as William Karl Kappel and Handong Li. These collaborations have fostered an environment of innovation and shared expertise, driving the progression of various projects and patents in the realm of biotechnology.

Conclusion

Richard J. Mehigh exemplifies the spirit of innovation through his substantial contributions to biochemistry and protein research. His patents and collaborative efforts at Sigma-Aldrich Co. LLC underscore the importance of teamwork and creativity in advancing scientific knowledge. As the field continues to evolve, Mehigh's work will undoubtedly have a lasting impact on the methodologies used in cellular extraction and purification techniques.