The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 21, 2010
Filed:
Jun. 12, 2003
Ronald A. Hernan, Ballwin, MO (US);
Richard J. Mehigh, St. Louis, MO (US);
Ian R. Brockie, St. Louis, MO (US);
Elizabeth Jenkins, Sherman, IL (US);
Ronald A. Hernan, Ballwin, MO (US);
Richard J. Mehigh, St. Louis, MO (US);
Ian R. Brockie, St. Louis, MO (US);
Elizabeth Jenkins, Sherman, IL (US);
Sigma-Aldrich, Co., St. Louis, MO (US);
Abstract
This invention describes a process for separating a fusion protein or polypeptide in the form of its precursor from a mixture containing said fusion protein and impurities, which comprises contacting said fusion protein with a resin containing immobilized metal ions, said fusion protein covalently operably linked directly or indirectly to an immobilized metal ion-affinity peptide, binding said fusion protein to said resin, and selectively eluting said fusion protein from said resin.