Location History:
- Gaithersburg, MD (US) (2011)
- Lansdowne, PA (US) (2010 - 2015)
Company Filing History:
4 out of 2,597 
1 out of 16,083 Years Active: 2010-2015
Title: Richard G Carroll: Innovator in Immunotherapy
Introduction
Richard G Carroll is a prominent inventor based in Lansdowne, PA (US). He has made significant contributions to the field of immunotherapy, particularly in the modulation of regulatory T cells. With a total of 5 patents, his work has paved the way for advancements in treating autoimmune responses and enhancing transplant success.
Latest Patents
One of Carroll's latest patents focuses on "Regulatory T cells and their use in immunotherapy and suppression of autoimmune responses." This invention is based on a strong correlation between regulatory T cells (Treg cells) and the suppression of cytotoxic T cell responses. The patent provides methods for producing ex vivo activated and culture-expanded isolated CD4CD25 suppressor Treg cells. These cells are crucial for preventing or suppressing immune reactions in hosts, particularly in humans, and include applications for autoimmune responses. The resulting ex vivo culture-expanded Treg cells offer a sufficient quantity of otherwise low numbers of such cells, possessing long-term suppressor capabilities for therapeutic uses. This includes preventing, suppressing, blocking, or inhibiting the rejection of transplanted tissue in human or animal hosts, as well as protecting against graft versus host disease. Additionally, Carroll's patent on "Modulation of regulatory T cells by human IL-18" relates to compositions and methods for modulating the presence and activity of regulatory T cells in subjects.
Career Highlights
Throughout his career, Richard G Carroll has worked with esteemed institutions, including the University of Pennsylvania and the United States Navy. His innovative research has significantly impacted the field of immunotherapy, leading to advancements that benefit patients with autoimmune diseases and those undergoing transplants.
Collaborations
Carroll has collaborated with notable figures in the field, including Carl H June and Bruce L Levine. These partnerships have further enhanced the scope and impact of his research.
Conclusion
Richard G Carroll's contributions to immunotherapy through his patents and collaborations have established him as a key figure in the field. His work continues to influence the development of treatments that improve patient outcomes in various medical scenarios.