Renuka Pillutla

Title: Renuka Pillutla: Innovator in Peptide Therapeutics

Introduction

Renuka Pillutla is a notable inventor based in Bridgewater, NJ (US), recognized for her contributions to the field of peptide therapeutics. With a total of three patents to her name, she has made significant strides in the development of innovative solutions for medical applications.

Latest Patents

One of her latest patents focuses on insulin and IGF-1 receptor agonists and antagonists. This invention discloses peptide sequences capable of binding to insulin and/or insulin-like growth factor receptors, exhibiting either agonist or antagonist activity. The invention identifies at least two different binding sites present on these receptors, which selectively bind the peptides. As agonists, these peptides may serve as therapeutics to supplement or replace endogenous peptide hormones. Additionally, the antagonist peptides may also be developed for therapeutic purposes. Another significant patent involves a modified phage display method for detecting and identifying target and target binders. This method transforms host cells with two separate phages of a target or target library and a target-binder library, allowing for the selection that eliminates non-paired targets and binders. This invention also encompasses antibodies that bind to complexes of target and target binders, nucleic acids encoding these peptides, and the use of sequence information for target validation using in silico approaches. Furthermore, it relates to diagnostics and therapeutics employing the disclosed peptides or polynucleotides, with applications in small molecule drug discovery and high throughput drug screening.

Career Highlights

Throughout her career, Renuka Pillutla has worked with various companies, including Antyra Inc. Her innovative work has positioned her as a key figure in the development of peptide-based therapeutics.

Collaborations

Renuka has collaborated with notable individuals in her field, including Renee Brissette and Arthur J Blume. These collaborations have contributed to her success and the advancement of her research.

Conclusion

Renuka Pillutla's work in peptide therapeutics showcases her innovative spirit and dedication to advancing medical science. Her patents reflect her commitment to developing solutions that can significantly impact healthcare.