The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 2005
Filed:
Sep. 24, 2001
Renuka Pillutla, Bridgewater, NJ (US);
Renee Brissette, Edison, NJ (US);
Arthur J. Blume, Annandale, NJ (US);
Lauge Schäffer, 2100-DK Copenhagen Ø, DK;
Jakob Brandt, 2700-DK Broenshoej, DK;
Neil I. Goldstein, Maplewood, NJ (US);
Jane Spetzler, 2100-DK Copenhagen Ø, DK;
Søren Østergaard, 2700-DK Broenshoej, DK;
Per Hertz Hansen, 2800-DK Lyngby, DK;
Renuka Pillutla, Bridgewater, NJ (US);
Renee Brissette, Edison, NJ (US);
Arthur J. Blume, Annandale, NJ (US);
Lauge Schäffer, 2100-DK Copenhagen Ø, DK;
Jakob Brandt, 2700-DK Broenshoej, DK;
Neil I. Goldstein, Maplewood, NJ (US);
Jane Spetzler, 2100-DK Copenhagen Ø, DK;
Søren Østergaard, 2700-DK Broenshoej, DK;
Per Hertz Hansen, 2800-DK Lyngby, DK;
Other;
Abstract
Peptide sequences capable of binding to insulin and/or insulin-like growth factor receptors with either agonist or antagonist activity and identified from various peptide libraries are disclosed. This invention also identifies at least two different binding sites, which are present on insulin and insulin-like growth factor receptors, and which selectively bind the peptides of this invention. As agonists, certain of the peptides of this invention may be useful for development as therapeutics to supplement or replace endogenous peptide hormones. The antagonists may also be developed as therapeutics.