This inventor holds 3 USPTO granted patents and 1 EPO patent. Top assignee: California Institute of Technology. Active years: 2008-2013.
Location History:
- Clark, NJ (US) (2008 - 2010)
- Pasadena, CA (US) (2013)
Company Filing History:
Years Active: 2008-2013
Title: The Innovative Contributions of Raymond Doss
Introduction
Raymond Doss is a notable inventor based in Clark, NJ (US). He has made significant contributions to the field of DNA recognition and binding through his innovative patents. With a total of 3 patents, Doss has developed methods and compositions that have the potential to impact gene transcription and therapeutic applications.
Latest Patents
One of Doss's latest patents is titled "Alternative heterocycles for DNA recognition." This patent provides methods and compositions for forming complexes between double-stranded DNA (dsDNA) and novel oligomers that comprise fused six-membered rings. By selecting appropriate target sequences and oligomers, these complexes can achieve high association constants. The formation of these complexes can be utilized for identifying specific dsDNA sequences, inhibiting gene transcription, and serving as a therapeutic approach for inhibiting the proliferation of undesired cells or modulating the expression of specific genes.
Another significant patent by Doss is focused on "DNA-binding polymers." This invention outlines methods and compositions for creating complexes between dsDNA and novel DNA-binding polymers that contain N-terminal thiophene moieties, which exhibit selectivity for T-A base pairs. Similar to his previous work, the appropriate choice of target sequences and DNA-binding polymers allows for the formation of complexes with high association constants. These complexes can also be used for identifying specific dsDNA sequences, inhibiting gene transcription, and providing therapeutic benefits.
Career Highlights
Raymond Doss is affiliated with the California Institute of Technology, where he continues to advance his research and innovations. His work has garnered attention for its potential applications in biotechnology and medicine.
Collaborations
Doss has collaborated with esteemed colleagues such as Peter B Dervan and Michael Marques, contributing to the advancement of research in DNA recognition and binding.
Conclusion
Raymond Doss's innovative patents and research contributions have the potential to significantly impact the fields of genetics and therapeutics. His work exemplifies the importance of innovation in addressing complex biological challenges.