The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 03, 2013

Filed:

Mar. 04, 2004
Applicants:

Peter B. Dervan, San Marino, CA (US);

Christoph A. Briehn, Obertshausen, DE;

Dorte Renneberg, Bern, CH;

Philipp Weyermann, Siassach, CH;

Raymond Doss, Pasadena, CA (US);

Michael Marques, San Mateo, CA (US);

Inventors:

Peter B. Dervan, San Marino, CA (US);

Christoph A. Briehn, Obertshausen, DE;

Dorte Renneberg, Bern, CH;

Philipp Weyermann, Siassach, CH;

Raymond Doss, Pasadena, CA (US);

Michael Marques, San Mateo, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 235/18 (2006.01); C07D 471/14 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods and compositions are provided for forming complexes between dsDNA and novel oligomers comprising fused six-membered rings. By appropriate choice of target sequences and oligomers, complexes comprising oligomer-DNA are obtained with high association constants. The formation of complexes can be used for identification of specific dsDNA sequences, for inhibiting gene transcription, and as a therapeutic for inhibiting proliferation of undesired cells or modulation of expression of specific genes.


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