Company Filing History:
Years Active: 2007-2009
Title: Ratna Ray: Innovator in Hepatitis C Research
Introduction
Ratna Ray is a distinguished inventor based in Saint Louis, MO (US). She has made significant contributions to the field of medical research, particularly in the study of hepatitis C virus and liver fibrosis. With a total of 2 patents, her work has the potential to impact therapeutic approaches for hepatic diseases.
Latest Patents
One of her latest patents is titled "Compositions and methods for generation of infectious hepatitis C virus in immortalized human hepatocytes." This invention provides a cell line capable of producing infectious hepatitis C virus 1a (HCV 1a) particles in culture. The patent discloses compositions and methods for an HCV 1a (clone H77) transfected immortal human hepatocyte (IHH) that can generate infectious HCV 1a virus particles. Additionally, it outlines methods for using the cell line or HCV 1a virus particles derived from it to screen for potential therapeutic agents that interfere with HCV 1a virus propagation, aiming to treat hepatic disease.
Another significant patent is the "Method of manufacturing a stellate cell death factor." This invention provides compositions and methods for selectively inhibiting the proliferation of stellate cells, which are crucial for the development of liver fibrosis following liver injury. The patent describes conditioned media from immortalized hepatocytes as containing a death factor that induces apoptosis of activated liver stellate cells. This pro-apoptotic activity is associated with an 80 kDa protein linked to a fetuin peptide sequence and an albumin peptide sequence.
Career Highlights
Ratna Ray is affiliated with Saint Louis University, where she conducts her research and develops her innovative ideas. Her work has garnered attention in the scientific community, contributing to advancements in understanding liver diseases and potential treatments.
Collaborations
She collaborates with notable colleagues, including Ranjit Ray and Arnab Basu, who share her commitment to advancing medical research.
Conclusion
Ratna Ray's innovative contributions to hepatitis C research and liver fibrosis highlight her role as a leading inventor in the medical field. Her patents reflect her dedication to finding solutions for complex health issues, paving the way for future advancements in therapeutic strategies.