The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2009

Filed:

Aug. 17, 2006
Applicants:

Ratna Ray, Saint Louis, MO (US);

Ranjit Ray, Saint Louis, MO (US);

Arnab Basu, Newton Lower Falls, MA (US);

Tatsuo Kanda, Chiba, JP;

Inventors:

Ratna Ray, Saint Louis, MO (US);

Ranjit Ray, Saint Louis, MO (US);

Arnab Basu, Newton Lower Falls, MA (US);

Tatsuo Kanda, Chiba, JP;

Assignee:

Saint Louis University, Saint Louis, MO (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/02 (2006.01); A01N 63/00 (2006.01); A61K 39/00 (2006.01); A61K 39/12 (2006.01); A61K 39/29 (2006.01); A61K 39/275 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a cell line capable producing infectious hepatitis C virus 1a (HCV 1a) particles in culture. Disclosed are compositions and methods for an HCV 1a (clone H77) transfected immortal human hepatocyte (IHH) capable of generating infectious HCV 1a virus particles in culture. Also disclosed are methods of using the cell line, or HCV 1a virus particles derived from said cell line, to screen for potential therapeutic agents which interfere with HCV 1a virus propagation to treat hepatic disease.


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