Company Filing History:
Years Active: 2002-2006
Title: Innovations of Qinjian Zhao in Vaccine Development
Introduction
Qinjian Zhao is a notable inventor based in Ambler, PA, who has made significant contributions to the field of vaccine development. With a total of two patents to his name, Zhao's work focuses on improving the efficacy and stability of vaccines against various infectious agents.
Latest Patents
One of Zhao's latest patents is for a recombinant hepatitis B surface antigen. This invention provides an improved rHBsAg that exhibits higher antigenicity and immunogenicity than previously known in the art. The method of making this improved rHBsAg is also detailed in the patent. The enhanced HBsAg is utilized to create vaccines that require lower amounts of active ingredients while offering higher immunogenicity. Additionally, it allows for the development of combination vaccines that provide protective immunization against hepatitis B virus and other infectious agents.
Another significant patent by Zhao is related to the process for making human papillomavirus virus-like particles (VLPs) with improved properties. In this invention, the VLPs undergo various maturation conditions, including incubation at higher temperatures and exposure to soluble metals or thios-oxidation. The resultant matured VLPs are more stable and can be used to formulate vaccines with increased shelf life and higher potency.
Career Highlights
Qinjian Zhao is currently employed at Merck & Company, Inc., where he continues to innovate in the field of vaccine research and development. His work has the potential to significantly impact public health by improving vaccine formulations.
Collaborations
Zhao collaborates with esteemed colleagues such as Shilu Wu and Walter E Manger, contributing to a dynamic research environment that fosters innovation and advancement in vaccine technology.
Conclusion
Qinjian Zhao's contributions to vaccine development through his patents demonstrate his commitment to enhancing public health. His innovative approaches to improving vaccine efficacy and stability are paving the way for more effective immunization strategies.