Company Filing History:
Years Active: 1997-2011
Title: PoJen Shih: Innovator in Peptide-Enhanced Transfections
Introduction
PoJen Shih is a notable inventor based in Columbia, MD (US). He has made significant contributions to the field of biotechnology, particularly in the area of transfection technologies. With a total of 5 patents to his name, Shih's work has advanced the methods used for delivering genetic material into cells.
Latest Patents
One of PoJen Shih's latest patents focuses on peptide-enhanced transfections. This invention provides compositions that are useful for transfecting eukaryotic cells. The compositions comprise nucleic acid complexes with peptides, which may be covalently coupled to a nucleic acid-binding group, along with cationic lipids or dendrimers as transfection agents. The invention also includes transfection compositions where a peptide is covalently linked to the transfection agent, such as lipid, cationic lipid, or dendrimer. The inclusion of peptides or modified peptides in these compositions results in enhanced transfection efficiency. Additionally, methods for preparing these transfection compositions and their use as intracellular delivery agents and extracellular targeting agents are disclosed.
Career Highlights
PoJen Shih is currently associated with Life Technologies Corporation, where he continues to innovate in the field of biotechnology. His work has been instrumental in developing new methods for genetic material delivery, which has implications for research and therapeutic applications.
Collaborations
Some of his notable coworkers include Pamela Hawley-Nelson and Joel A Jessee. Their collaborative efforts contribute to the advancements in the technologies being developed at Life Technologies Corporation.
Conclusion
PoJen Shih's contributions to peptide-enhanced transfections represent a significant advancement in biotechnology. His innovative work continues to influence the field and improve the efficiency of genetic material delivery methods.