Phyllis S Goldman

Title: Phyllis S Goldman: Innovator in Biochemical Research

Introduction

Phyllis S Goldman is a distinguished inventor based in Bothell, WA (US), known for her significant contributions to biochemical research. With a total of three patents to her name, she has made remarkable advancements in the field of human poly(ADP-ribose) polymerase and its applications.

Latest Patents

Goldman's latest patents include groundbreaking work on human poly(ADP-ribose) polymerase 2 materials and methods. This invention provides novel human poly(ADP-ribose) polymerase (hPARP2) polypeptides, polynucleotides encoding these polypeptides, expression constructs, and host cells transformed with these constructs. Additionally, her work outlines methods for producing hPARP2 polypeptides and antibodies that are immunoreactive with them. Furthermore, she has developed methods for identifying specific binding partners of hPARP2, particularly those that modulate its biological activity. Another significant patent involves PARP inhibitors, which includes compounds with a bicyclic aryl moiety, such as 2H-phthalazin-1-one, and methods for their production and use.

Career Highlights

Throughout her career, Goldman has worked with notable companies such as Icos Corporation and Deltagen Research Labs, LLC. Her experience in these organizations has contributed to her expertise and innovative capabilities in the field of biochemistry.

Collaborations

Goldman has collaborated with esteemed colleagues, including David L McElligott and Erik Christenson, further enhancing her research and development efforts.

Conclusion

Phyllis S Goldman is a prominent figure in biochemical innovation, with a focus on human poly(ADP-ribose) polymerase and its inhibitors. Her patents reflect her dedication to advancing scientific knowledge and improving therapeutic methods.