Philip Edward Coughlin

Title: The Innovations of Philip Edward Coughlin

Introduction

Philip Edward Coughlin is a notable inventor based in Wilmington, DE (US). He has made significant contributions to the field of protein structure determination through his innovative patents. With a total of 4 patents, Coughlin's work has advanced the understanding of biological macromolecules.

Latest Patents

One of his latest patents is focused on the development of 13C, 15N, and 2H labeled proteins for NMR structure determinations and their preparation. This invention addresses the challenge of determining the three-dimensional structure of proteins. It provides methods for rapidly determining protein structure by NMR, simplifying NMR spectra using labeled proteins prepared from specifically isotopically labeled amino acids. These amino acids contain at least two isotopes of 13C, 15N, and 2H in the backbone. The methods also include the cultivation of a microbial culture containing these labeled amino acids.

Career Highlights

Coughlin is currently associated with Martek Biosciences Corporation, where he continues to innovate in the field of biochemistry. His work has been instrumental in enhancing the techniques used for protein structure analysis.

Collaborations

Throughout his career, Coughlin has collaborated with notable colleagues, including Frank Elbert Anderson, III and Jonathan Miles Brown. These collaborations have contributed to the advancement of research in his field.

Conclusion

Philip Edward Coughlin's contributions to the field of protein structure determination through his patents have had a lasting impact on biochemistry. His innovative approaches continue to influence research and development in this important area.