The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 22, 2002
Filed:
Jul. 10, 2000
Frank Elbert Anderson, III, Gaithersburg, MD (US);
Jonathan Miles Brown, Silver Spring, MD (US);
Philip Edward Coughlin, Wilmington, DE (US);
Steven William Homans, Dundee, GB;
Charles Tobias Weller, Fife, GB;
Carrie Ann Zimmerman-Wilson, Ellicott City, MD (US);
Eddie James Oliver, Jr., Takoma Park, MD (US);
Martek Biosciences Corporation, Columbia, MD (US);
Abstract
This invention is concerned with determining the three-dimensional structure of biological macromolecules such as proteins. In particular, it is concerned with methods for rapidly determining protein structure by NMR, by providing methods for simplifying NMR spectra using labeled proteins prepared from specifically isotopically labeled amino acids having at least two isotopes of 13C, 15N and 2H in the backbone, and methods for making these labeled proteins, e.g., by cultivation of a microbial culture containing said labeled amino acids.