Charles Tobias Weller

Title: Innovations of Charles Tobias Weller

Introduction

Charles Tobias Weller is a notable inventor based in Fife, GB. He has made significant contributions to the field of biological macromolecules, particularly in the area of protein structure determination. With a total of 4 patents, Weller's work has advanced the methods used in nuclear magnetic resonance (NMR) spectroscopy.

Latest Patents

Weller's latest patents include the invention of 13C, 15N, and 2H labeled proteins for NMR structure determinations and their preparation. This invention focuses on determining the three-dimensional structure of biological macromolecules, such as proteins. It provides methods for rapidly determining protein structure by NMR, simplifying NMR spectra using labeled proteins prepared from specifically isotopically labeled amino acids. These amino acids contain at least two isotopes of 13C, 15N, and 2H in the backbone. The methods also include the cultivation of a microbial culture containing these labeled amino acids to produce the labeled proteins.

Career Highlights

Weller is associated with Martek Biosciences Corporation, where he has been instrumental in developing innovative solutions in the field of protein research. His work has not only contributed to scientific advancements but has also had practical applications in various industries.

Collaborations

Some of Weller's notable coworkers include Frank Elbert Anderson, III, and Jonathan Miles Brown. Their collaborative efforts have further enhanced the research and development initiatives at Martek Biosciences Corporation.

Conclusion

Charles Tobias Weller's contributions to the field of protein structure determination through his innovative patents have made a lasting impact. His work continues to influence research in biological macromolecules and NMR spectroscopy.