Location History:
- Baltimore, MD (US) (1995 - 1998)
- Chevy Chase, MD (US) (2021 - 2022)
- Silver Spring, MD (US) (2000 - 2023)
Company Filing History:
Years Active: 1995-2025
Title: Innovations by Jonathan Miles Brown: A Pioneer in Oligonucleotide Research
Introduction
Jonathan Miles Brown, an accomplished inventor based in Silver Spring, MD, has made significant contributions to the field of biotechnology with his 12 patents. His work primarily focuses on the development of innovative oligonucleotide technologies that aim to enhance therapeutic efficacy and reduce unwanted side effects in medical applications.
Latest Patents
Among his latest inventions is a patent for "Multimeric oligonucleotides having decreased kidney clearance." This invention involves methods of administering multimeric oligonucleotides comprised of monomeric subunits linked together, resulting in a molecular weight of at least 45 kD. These characteristics help to minimize clearance through glomerular filtration, thereby improving the pharmacokinetic profile of therapeutic agents.
Another notable patent is for "Defined multi-conjugates oligonucleotides." This innovation allows the creation of defined multi-conjugate oligonucleotides with predetermined sizes and compositions. These oligonucleotides, particularly in the form of multi-conjugate siRNA, offer enhanced intracellular delivery and multi-gene silencing capabilities. They are potentially valuable for reducing gene expression, conducting biological research, or treating various medical conditions.
Career Highlights
Throughout his career, Jonathan has worked with esteemed organizations, including Martek Biosciences Corporation and Mpeg La, L.L.C. His experiences in these companies have contributed to his deep understanding of biotechnology and patentable innovations related to oligonucleotides.
Collaborations
Jonathan's journey in the innovation landscape has been further enriched by collaborations with eminent professionals, such as Frank Elbert Anderson, III, and Philip Edward Coughlin. These partnerships have fostered an exchange of ideas and propelled the advancement of research in oligonucleotide technologies.
Conclusion
Jonathan Miles Brown's inventive spirit and relentless pursuit of innovation have led to groundbreaking advancements in the field of biotechnology. With his 12 patents and ongoing contributions, he stands at the forefront of oligonucleotide research, paving the way for future therapeutic innovations that may transform medical treatments.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.