Company Filing History:
Years Active: 2001-2025
Title: Innovations of Philip A. Leighton: A Pioneer in Transgenic Research
Introduction
Philip A. Leighton, located in San Francisco, CA, is an accomplished inventor with a notable portfolio of 12 patents. His innovative contributions to the field of transgenic animals and antibody diversification have paved the way for advancements in biotechnology and medical research.
Latest Patents
Among his latest patents is the groundbreaking invention related to the camelization of a human variable domain by gene conversion. This patent discloses a transgenic animal that utilizes gene conversion for antibody diversification. It involves B cells in which the endogenous immunoglobulin heavy chain locus comprises a functional immunoglobulin heavy chain gene encoding a human heavy chain variable domain, alongside a range of pseudogenes that facilitate nucleotide sequence donation through gene conversion. The invention enhances the potential for producing antibodies with camelizing amino acid substitutions.
Another significant patent is for a transgenic chicken featuring an inactivated immunoglobulin gene. This invention not only provides the basis for creating transgenic chickens with designed immunoglobulin genes but also includes cells and targeting vectors necessary for the development of such transgenic organisms.
Career Highlights
Philip has made substantial strides in his career through his roles in prominent organizations like Crystal Bioscience Inc. and the University of California. His work in these entities showcases his dedication to advancing scientific understanding in genetic engineering and transgenic applications.
Collaborations
Collaboration has been a key aspect of Philip A. Leighton's career. He has worked alongside notable colleagues such as William Don Harriman and Robert Etches, forming partnerships that have fostered innovative ideas and facilitated substantial advances in their respective fields.
Conclusion
Philip A. Leighton stands as a distinguished inventor whose groundbreaking patents and collaborations significantly contribute to the realm of biotechnology. His innovative spirit and commitment to research continue to inspire future developments in transgenic science and antibody diversification.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.