The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 15, 2021
Filed:
Aug. 24, 2016
Applicant:
Crystal Bioscience Inc., San Diego, CA (US);
Inventors:
William Don Harriman, Alameda, CA (US);
Robert Etches, Oakland, CA (US);
Philip A. Leighton, San Francisco, CA (US);
Assignee:
CRYSTAL BIOSCIENCE INC., San Diego, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A01K 67/027 (2006.01); C12N 15/85 (2006.01); C07K 16/00 (2006.01); C07K 16/46 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0278 (2013.01); C07K 16/00 (2013.01); C07K 16/46 (2013.01); C12N 15/8509 (2013.01); A01K 2217/072 (2013.01); A01K 2217/206 (2013.01); A01K 2227/30 (2013.01); A01K 2267/01 (2013.01); C07K 2317/21 (2013.01); C07K 2317/23 (2013.01); C12N 2800/30 (2013.01); C12N 2830/40 (2013.01);
Abstract
This disclosure provides, among other things, a transgenic animal and a method of using the same to make antibodies that have a common light chain. In certain embodiments, the transgenic animal may comprising a genome comprising a common light chain transgene, wherein the common light chain transgene comprises a non-immunoglobulin light-chain promoter and a common light-chain coding sequence. In certain embodiments, the common light chain is constitutively expressed.