For the Inventor, By the Inventor

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Emeryville, CA, United States of America

Crystal Bioscience Inc.

Calculating rank

USPTO Granted Patents = 30

% Expired Patents = 10.0

EPO Patents = 6

Trademarks = 4

Forward Citations = 126

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9 inventors (with patents filed for the assignee):

William Don Harriman (28 out of 34 patents)

Robert Etches (17 out of 22 patents)

Philip A Leighton (16 out of 17 patents)

4. Shelley Izquierdo (3 out of 6 patents)

5. Phil Leighton (3 out of 3 patents)

6. Christel Iffland (2 out of 8 patents)

7. Marie-Cecile Van De Lavoir (2 out of 3 patents)

8. Ellen Collarini (2 out of 2 patents)

9. Shreya Pramanick (1 out of 1 patent)

Core Competencies:

Transgenic Chicken

Antibody Diversification

Gene Conversion

Immunoglobulin Gene

CDR Stabilization

In Vivo Methods

Avian Gonocytes

Heavy Chain Variable Domain

GIPR Antibodies

Anti-CD38 Antibody

Anti-B7-H3 Antibody

Microdrop Composition

30 patents: Sort by Forward Citations

1. 12588664 - Production of antibodies by modification of an autonomous heavy chain variable domain by gene conversion (2026-03-31),

2. 12583930 - HUMAN GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR (GIPR) ANTIBODIES AND METHODS OF USE THEREOF TO INHIBIT GIP RECEPTOR AND SIGNALING (2026-03-24),

3. 12568940 - TRANSGENIC CHICKEN HAVING AN ENDOGENOUS IMMUNOGLOBULIN HEAVY CHAIN GENE IN WHICH THE IGY CH1 CODING SEQUENCE IS FUNCTIONALLY DELETED (2026-03-10),

4. 12543710 - TRANSGENIC ANIMAL FOR PRODUCING DIVERSIFIED ANTIBODIES THAT HAVE THE SAME LIGHT CHAIN II (2026-02-10),

5. 12534537 - ANTI-CD38 ANTIBODY AND METHODS OF USE THEREOF (2026-01-27),

6. 12441802 - Anti-B7-H3 antibody and methods of use thereof (2025-10-14),

7. 12428471 - Transgenic chicken that makes antibodies with long CDR-H3S stabilized by multiple disulfide bridges and diversified by gene conversion (2025-09-30),

8. 12408640 - Transgenic animal for producing diversified antibodies that have the same light chain I (2025-09-09),

9. 12102070 - Camelization of a human variable domain by gene conversion (2024-10-01),

10. 11602136 - In vivo method for generating diversity in a protein scaffold (2023-03-14),

11. 11542319 - Transgenic chicken comprising an inactivated immunoglobulin gene (2023-01-03),

12. 11337409 - Transgenic animal for producing diversified antibodies that have the same light chain I (2022-05-24),

13. 11033009 - Transgenic chicken for production of antibodies having a common light chain (2021-06-15),

14. 10689433 - Transgenic chicken comprising an inactivated immunoglobulin gene (2020-06-23),

15. 10687519 - Transgenic animal for production of antibodies having minimal CDRs (2020-06-23),

Company Overview

Crystal Bioscience Inc. is a biotechnology company based in Emeryville, California, specializing in the development of innovative solutions for protein production and therapeutic applications. The company focuses on harnessing advanced technologies to create high-quality proteins for research and therapeutic use, particularly in the fields of drug discovery and vaccine development. With a commitment to scientific excellence, Crystal Bioscience aims to address critical challenges in the life sciences sector through its proprietary platforms and methodologies.

Profile summary synthesized from public USPTO records and patent filings.

Company Badge

USPTO Data Jan 1 1976 - Oct 27 2026

30 Patents

#19 in Emeryville, CA

#2,686 in California

#11,288 in US

#21,924 in the World

Emeryville, CA, United States of America

Crystal Bioscience Inc.

Forward Citations = 126

9 inventors:

William Don Harriman (28 out of 34 patents)

Robert Etches (17 out of 22 patents)

Philip A Leighton (16 out of 17 patents)

4. Shelley Izquierdo (3 out of 6 patents)

5. Phil Leighton (3 out of 3 patents)

IDiyas Innovation Intelligence. (2026). Company Patent Portfolio: Crystal Bioscience Inc.. Retrieved from https://idiyas.com/company/crystal-bioscience

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Data Sources: USPTO Patent Grant XML, Patent Center, EPO & CIPO • Normalized by IDiyas Innovation Graph. Methodology & provenance architecturePlease report any incorrect information to [email protected]

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