Raleigh, NC, United States of America

Pauline Wanjiku Ondachi

USPTO Granted Patents = 6 


 

Average Co-Inventor Count = 3.0

ph-index = 1

Forward Citations = 1(Granted Patents)


Location History:

  • Raleigh, NC (US) (2010 - 2016)
  • Research Triangle Park, NC (US) (2022)

Company Filing History:


Years Active: 2010-2022

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6 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Pauline Wanjiku Ondachi

Introduction

Pauline Wanjiku Ondachi is a notable inventor based in Raleigh, NC, who has made significant contributions to the field of pharmacology. With a total of six patents to his name, Ondachi's work focuses on developing compounds that target various receptors in the brain, offering potential treatments for a range of mental health and addiction disorders.

Latest Patents

Among his latest patents, Ondachi has developed substituted 1,2,3,4-tetrahydroisoquinolines as kappa opioid antagonists. These potent opioid receptor antagonists are designed for use as pharmacotherapies to treat conditions such as depression, anxiety, schizophrenia, eating disorders, and addictions to substances like cocaine, methamphetamine, nicotine, alcohol, and opiates. His research provides valuable insights into the development of selective kappa opioid receptor antagonist compounds, pharmaceutical compositions, and their therapeutic applications.

Another significant patent involves nicotinic receptor compounds. This patent outlines compounds and methods for preparing substances that can act as agonists or antagonists of nicotinic receptors. The pharmaceutical compositions derived from these compounds may include additional therapeutic agents, offering methods of treatment for conditions responsive to nicotinic receptor activity, such as nicotine dependence.

Career Highlights

Ondachi has worked with esteemed organizations such as the Research Triangle Institute and North Carolina State University. His career reflects a commitment to advancing scientific knowledge and developing innovative solutions in the field of pharmacology.

Collaborations

Throughout his career, Ondachi has collaborated with notable colleagues, including Frank Ivy Carroll and Hernan A Navarro. These partnerships have contributed to the depth and breadth of his research endeavors.

Conclusion

Pauline Wanjiku Ondachi's innovative work in pharmacology, particularly in the development of compounds targeting opioid and nicotinic receptors, showcases his dedication to addressing critical health issues. His contributions continue to pave the way for new therapeutic options in treating addiction and mental health disorders.

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