The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2015

Filed:

Dec. 26, 2012
Applicants:

Research Triangle Institute, Research Triangle Park, NC (US);

The Regents of the University of Michigan, Ann Arbor, MI (US);

Virginia Commonwealth University, Richmond, VA (US);

Inventors:

Frank Ivy Carroll, Durham, NC (US);

Pauline Wanjiku Ondachi, Raleigh, NC (US);

Hernan A. Navarro, Chapel Hill, NC (US);

M. Imad Damaj, Richmond, VA (US);

James H. Woods, Ann Arbor, MI (US);

Emily M. Jutkiewicz, Ann Arbor, MI (US);

Assignees:

RESEARCH TRIANGLE INSTITUTE, Research Triangle Park, NC (US);

THE REGENTS OF THE UNIVERSITY OF MICHIGAN, Ann Arbor, MI (US);

VIRGINIA COMMONWEALTH UNIVERSITY, Richmond, VA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/08 (2006.01);
U.S. Cl.
CPC ...
C07D 487/08 (2013.01);
Abstract

Compounds and compositions for promoting smoking cessation or decreasing tobacco use or nicotine addiction are provided. The compounds are 2'-fluoro-3′-(substituted phenyl) deschloroepibatidine analogs. The compounds have been found to modulate neuronal nicotine acetylcholine receptors and are useful in methods for the treatment of conditions or disorders influenced by the modulation of neuronal nicotinic acetylcholine receptors.


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