Paul S Peluso

Title: **Paul S Peluso: Innovator in Polymerase Technology**

Introduction

Paul S Peluso is a prominent inventor based in San Carlos, California, with an impressive portfolio of 26 patents. He is known for his contributions to the field of biotechnology, particularly in the area of polymerases and their applications in sequencing, DNA replication, and amplification.

Latest Patents

Among his latest patents is a significant innovation titled "Polymerases for nucleotide analogue incorporation." This invention focuses on compositions that enhance the entry of nucleotide analogues into the active sites of polymerases, facilitating improved coordination with these analogues. The patent also covers methods for synthesizing these specialized polymerases and utilizing them in sequencing and DNA processes, along with kinetic models and computer-implemented methods that optimize polymerase activity.

Another noteworthy patent is "Articles having localized molecules disposed thereon." This invention outlines methods for creating substrates with designated active chemical regions, which involve employing substrate elements to help localize active chemical groups precisely. These methods encompass a range of processes, including optical, chemical, and mechanical techniques, to manage the deposition and activation of chemical groups in chosen regions of the substrates.

Career Highlights

Paul S Peluso currently works at Pacific Biosciences of California, Inc., a leading company in genomic sequencing technology. His work at the company has significantly advanced the understanding and application of polymerases, contributing to innovations that have impacted the biotechnology landscape.

Collaborations

Throughout his career, Peluso has collaborated with several talented individuals, including colleagues David R Rank and Daniel Bernardo Roitman. These collaborations have fostered a productive environment for research and development, enabling the creation of cutting-edge solutions in the field of molecular biology.

Conclusion

Paul S Peluso's contributions to polymerase technology exemplify his commitment to innovation and advancement in biotechnology. With a strong patent portfolio and a collaborative approach to research, he continues to make significant strides in the development of methods and tools that enhance genetic analysis and biotechnological applications.