Location History:
- Weston, MA (US) (2012 - 2017)
- Natick, MA (US) (2016 - 2019)
- Wellesley, MA (US) (2007 - 2022)
- Cambridge, MA (US) (2023)
Company Filing History:
26 out of 850 
6 out of 60 
Years Active: 2007-2023
Title: Paul E. Fleming: Innovator in Activin Receptor-Like Kinase Research
Introduction
Paul E. Fleming, based in Wellesley, Massachusetts, is a prominent inventor with an impressive portfolio of 32 patents. His contributions to the field of biochemistry and pharmacology, particularly focusing on activin receptor-like kinase (ALK), have positioned him as a significant figure in medical research.
Latest Patents
Among his recent patents are two noteworthy inventions centered on inhibitors of activin receptor-like kinase. The first patent details compounds that inhibit ALK2 and its mutants, along with pharmaceutical compositions that include these compounds and methods for their use. The second patent expands upon this theme with substituted pyrrolopyridines that also serve as inhibitors of ALK2 and its variants, showcasing innovative approaches to targeting this critical biological pathway.
Career Highlights
Paul has held pivotal roles at Millennium Pharmaceuticals and Blueprint Medicines Corporation, where he has driven forward research on small molecule inhibitors. His work has not only contributed to advancements in targeted therapies but has also underscored the importance of pharmaceutical innovations in treating various conditions influenced by ALK signaling pathways.
Collaborations
Throughout his career, Paul has collaborated with numerous esteemed professionals, including Zhan Shi and Jeffrey P. Ciavarri. These partnerships have facilitated significant research initiatives, allowing for the exchange of ideas and expertise in the development of novel therapeutic compounds.
Conclusion
Paul E. Fleming stands out as a remarkable inventor whose contributions continue to shape the landscape of pharmaceutical research. His patents reflect a dedication to innovation that promises to impact medical treatments significantly, and his collaborations further enhance the collective effort toward breakthroughs in health science.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.