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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10202365 B1

PDFFull Text
Date of Patent:
Feb. 12, 2019

Filed:

Feb. 05, 2016

2-(pyridin-3-yl)-pyrimidine derivatives as ret inhibitors

Applicant:

Blueprint Medicines Corporation, Cambridge, MA (US);

Inventors:

Natasja Brooijmans, Boston, MA (US);

Lucian V. DiPietro, Gloucester, MA (US);

Paul E. Fleming, Wellesley, MA (US);

Joseph L. Kim, Wayland, MA (US);

Steven Mark Wenglowsky, Cambridge, MA (US);

Yulian Zhang, Acton, MA (US);

Assignee:

BLUEPRINT MEDICINES CORPORATION, Cambridge, MA (US);

Attorney:

Finnegan, Henderson, Farabow, Garrett & Dunner, LLP

Primary Examiner:

Jeffrey H Murray

Int. Cl.
CPC ...
A61K 31/506 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 405/14 (2006.01); C07D 403/04 (2006.01); C07D 417/14 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 31/506 (2013.01); A61K 45/06 (2013.01); C07D 403/04 (2013.01); C07D 403/12 (2013.01); C07D 405/14 (2013.01); C07D 417/14 (2013.01);
Abstract

Described herein are compounds, such as compounds of Formula (I) and pharmaceutically acceptable salts thereof, that inhibit wild-type RET and its resistant mutants, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions, e.g., for treating a condition mediated by aberrant RET activity

Find Patent Forward Citations

Brooijmans, Natasja. (2019). 2-(pyridin-3-yl)-pyrimidine derivatives as ret inhibitors (U.S. Patent No. 10202365). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10202365

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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