Company Filing History:
Years Active: 2006-2014
Title: Innovator Spotlight: Paul A. Negulescu and His Contributions to Biological Research
Introduction: Paul A. Negulescu, based in Del Mar, California, is a notable inventor whose work has yielded three patents focused on advancements in biological assays. His innovations have significantly contributed to the field of biological research, particularly in understanding the biological properties of cells.
Latest Patents: Among his latest inventions are two pivotal patents that revolve around dual-compartment assay chambers. The first patent, titled "Multiwell Assay Apparatus and Method for Determining Biological Activity of Compounds," describes a device designed to characterize the biological properties of cells using a series of dual-compartment assay chambers. In these chambers, compartments are separated by a cell layer that permits ion flow, allowing for the examination of the cell layer's properties in response to experimental compounds by measuring electrical gradients.
The second patent, "Multiwell Plate Assembly for Use in High Throughput Assays," shares a similar concept. This innovation enhances the capabilities of high throughput assays, which are essential for evaluating the biological effects of various compounds on cell function with greater efficiency.
Career Highlights: Paul A. Negulescu has held positions at leading biotechnology companies such as Vertex Pharmaceuticals, Inc. and Invitrogen Corporation. His experience in these organizations has allowed him to work at the cutting edge of scientific research and product development, making substantial contributions to drug discovery processes.
Collaborations: Throughout his career, Negulescu has collaborated with other talented scientists and professionals, including coworkers Alec Tate Harootunian and Philip Emanuel Salzmann. These collaborations have enriched his research and fostered an environment of innovation in biological analysis techniques.
Conclusion: Paul A. Negulescu's contributions through his patents and professional endeavors illustrate his commitment to advancing biological research. With a focus on enhancing assays for the characterization of cells, his work supports the ongoing efforts in biotechnology to develop more effective therapies and improve our understanding of cellular mechanisms.
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