The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 30, 2007

Filed:

Mar. 31, 2004
Applicants:

Paul A. Negulescu, Del Mar, CA (US);

Alec T. Harootunian, San Diego, CA (US);

Philip E. Salzmann, Cardiff, CA (US);

Javier H. Flores, San Diego, CA (US);

James E. Sinclair, Carlsbad, CA (US);

Minh Vuong, San Diego, CA (US);

Ashvani K. Singh, San Diego, CA (US);

Fred F. Vangoor, San Diego, CA (US);

Inventors:

Paul A. Negulescu, Del Mar, CA (US);

Alec T. Harootunian, San Diego, CA (US);

Philip E. Salzmann, Cardiff, CA (US);

Javier H. Flores, San Diego, CA (US);

James E. Sinclair, Carlsbad, CA (US);

Minh Vuong, San Diego, CA (US);

Ashvani K. Singh, San Diego, CA (US);

Fred F. VanGoor, San Diego, CA (US);

Assignee:

Vertex Pharmaceutcals, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A device for characterizing the biological properties of cells can include a plurality of dual-compartment assay chambers wherein the compartments of each chamber are separated by a cell layer across which ions can flow. The biological properties of the cell layer in the presence or absence of experimental compounds can be determined by measuring an electrical gradient across the layer. A individual dual-compartment chamber of this type may be referred to as an 'Ussing chamber.'


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