Location History:
- Layfayette, CO (US) (1997 - 1998)
- Lafayette, CO (US) (2001 - 2014)
Company Filing History:
3 out of 110 
3 out of 138 
1 out of 672 
Years Active: 1997-2014
Title: The Innovative Contributions of Pamela Pavco
Introduction
Pamela Pavco is a distinguished inventor based in Lafayette, Colorado, known for her significant contributions to the field of gene expression modulation. With a total of nine patents to her name, she has made remarkable strides in the development of therapeutic and diagnostic applications.
Latest Patents
Among her latest patents is the invention titled "RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)." This invention focuses on methods and reagents that modulate gene expression across various applications, including therapeutic and diagnostic uses. It specifically involves synthetic chemically modified small nucleic acid molecules capable of mediating RNA interference against target nucleic acid sequences. Another notable patent is "RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)." This invention addresses the modulation of vascular endothelial growth factor and its receptor gene expression, which is crucial in the diagnosis and treatment of cancer and other proliferative diseases.
Career Highlights
Pamela has worked with prominent companies in the biotechnology sector, including Ribozyme Pharmaceuticals, Incorporated and Sirna Therapeutics, Inc. Her work has significantly impacted the development of innovative therapies that leverage RNA interference technology.
Collaborations
Throughout her career, Pamela has collaborated with notable professionals in her field, including James A McSwiggen and Jaime A Escobedo. These collaborations have further enhanced her research and development efforts.
Conclusion
Pamela Pavco's innovative work in gene expression modulation has paved the way for advancements in therapeutic and diagnostic applications. Her contributions continue to influence the biotechnology landscape, showcasing the importance of her inventions in addressing critical health challenges.