The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2006
Filed:
May. 03, 2002
Pamela Pavco, Lafayette, CO (US);
James Mcswiggen, Boulder, CO (US);
Dan Stinchcomb, Ft. Collins, CO (US);
Jaime Escobedo, Alamo, CA (US);
Pamela Pavco, Lafayette, CO (US);
James McSwiggen, Boulder, CO (US);
Dan Stinchcomb, Ft. Collins, CO (US);
Jaime Escobedo, Alamo, CA (US);
Sirna Therapeutics, Inc., Boulder, CO (US);
Chiron Corporation, Emeryville, CA (US);
Abstract
The present invention relates to nucleic acid molecules such as ribozymes, DNAzymes, and antisense which modulate the synthesis, expression and/or stability of an mRNA encoding one or more receptors of vascular endothelial growth factor, such as flt-1 and KDR. Nucleic acid molecules and methods for the inhibition of angiogenesis and treatment of cancer and ocular diseases are provided, optionally in conjunction with other therapeutic agents.