The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2001
Filed:
Sep. 30, 1999
Applicant:
Inventors:
Didier Betbeder, Aucamville, FR;
Roger Kravtzoff, Fourquevaux, FR;
Ignacio de Miguel, Plaisance du Touch, FR;
Sophie Sixou, Toulouse, FR;
Pamela Pavco, Lafayette, CO (US);
Thale Jarvis, Boulder, CO (US);
Assignee:
Biovector Therapeutics, S.A., Labege Cedex, FR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 7/18 ; C12Q 1/68 ; C07H 2/102 ; C07H 2/104 ; A61K 5/100 ;
U.S. Cl.
CPC ...
C12P 7/18 ; C12Q 1/68 ; C07H 2/102 ; C07H 2/104 ; A61K 5/100 ;
Abstract
The invention relates to an ionic conjugate, which is stable in a biological medium, and which is comprised of a particle vector with at least one cationic, nonliquid, hydrophilic nucleus and of polyanionic oligonucleotides. The invention further concerns the pharmaceutical compositions containing these conjugates and the use of a particle vector to carry the oligonucleotides to the cells.