Location History:
- Copenhaven, DK (2017)
- Seattle, WA (US) (2006 - 2018)
Company Filing History:
Years Active: 2006-2018
Title: Innovations by Pallavur V Sivakumar: Pioneering Advances in Cancer Research
Introduction
Pallavur V Sivakumar, based in Seattle, WA, has made significant contributions to the field of biomedical research through his extensive portfolio of 23 patents. His work focuses on novel therapeutic approaches, particularly in the modulation of immune responses and addressing neovascular disorders.
Latest Patents
Among his latest patents, two stand out for their innovative approaches. The first is titled "B7 family member zB7H6 and related compositions and methods." This patent discloses a newly identified member of the B7 family, zB7H6, which serves as a counter-receptor for the NK cell triggering receptor NKp30. This innovation includes methods and compositions for modulating NKp30-mediated NK cell activity, as well as developing anti-zB7H6 antibodies. The patent further explores antibody-drug conjugates that utilize anti-zB7H6 antibodies conjugated to therapeutic agents aimed at therapeutic effects against cells expressing zB7H6.
The second patent is focused on "Compositions and methods for inhibiting PDGFRbeta and VEGF-A." This patent describes antagonists for the PDGF receptor beta (PDGFRβ) and VEGF-A, alongside neutralizing antibodies targeting both molecules. This groundbreaking work also encompasses bispecific antibodies capable of neutralizing PDGFRβ and VEGF-A, with implications for treating neovascular disorders such as cancer and ocular diseases.
Career Highlights
Pallavur V Sivakumar is a key researcher at Zymogenetics, Inc., where he collaborates on innovative solutions in therapeutic development. His work has positioned him as a leading figure in the research community, significantly impacting cancer treatment and immune modulation.
Collaborations
Throughout his career, Sivakumar has worked closely with esteemed colleagues, including Wayne R Kindsvogel and Wenfeng Xu. These collaborations have enriched his research, leading to the development of novel therapeutic agents and comprehensive research methodologies that push the boundaries of current medical science.
Conclusion
As a dedicated innovator and researcher, Pallavur V Sivakumar continues to pave the way for advancements in medical treatments through his patents and collaborative efforts. His work at Zymogenetics, Inc. not only enhances understanding in the field of immune responses but also holds promise for future therapeutic implementations targeting critical health challenges.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.