The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 26, 2014
Filed:
Sep. 07, 2012
Kevin M. Klucher, Bellevue, WA (US);
Wayne R. Kindsvogel, Seattle, WA (US);
Pallavur V. Sivakumar, Seattle, WA (US);
Katherine E. Henderson, Seattle, WA (US);
Kevin M. Klucher, Bellevue, WA (US);
Wayne R. Kindsvogel, Seattle, WA (US);
Pallavur V. Sivakumar, Seattle, WA (US);
Katherine E. Henderson, Seattle, WA (US);
ZymoGenetics, Inc., Seattle, WA (US);
Abstract
IL-28A, IL-28B, IL-29, and certain mutants thereof have been shown to have antiviral activity on a spectrum of viral species. Of particular interest is the antiviral activity demonstrated on viruses that infect liver, such as hepatitis B virus and hepatitis C virus. In addition, IL-28A, IL-28B, IL-29, and mutants thereof do not exhibit some of the antiproliferative activity on hematopoietic cells that is observed with interferon treatment. Without the immunosuppressive effects accompanying interferon treatment, IL-28A, IL-28B, and IL-29 will be useful in treating immunocompromised patients for viral infections.